SAR405838

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TargetMol
Product Code: TAR-T6585
Supplier: TargetMol
CodeSizePrice
TAR-T6585-1mg1mg£107.00
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TAR-T6585-2mg2mg£137.00
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TAR-T6585-5mg5mg£179.00
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TAR-T6585-1mL1 mL * 10 mM (in DMSO)£204.00
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Quantity:
TAR-T6585-10mg10mg£251.00
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Quantity:
TAR-T6585-25mg25mg£425.00
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Quantity:
TAR-T6585-50mg50mg£592.00
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TAR-T6585-100mg100mg£814.00
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TAR-T6585-500mg500mg£1,572.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
MI-773 (SAR405838) is an orally available MDM2 antagonist with Ki of 0.88 nM. Phase 1.
CAS:
1303607-60-4
Formula:
C29H34Cl2FN3O3
Molecular Weight:
562.51
Pathway:
Apoptosis; Ubiquitination
Purity:
0.98
SMILES:
CC(C)(C)C[C@@H]1N[C@H]([C@H](c2cccc(Cl)c2F)[C@]11C(=O)Nc2cc(Cl)ccc12)C(=O)N[C@H]1CC[C@H](O)CC1
Target:
Mdm2; E1/E2/E3 Enzyme

References

Wang S, et al. Cancer Res. 2014, 74(20), 5855-5865.