NSC-207895

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TargetMol
Product Code: TAR-T6610
Supplier: TargetMol
CodeSizePrice
TAR-T6610-1mg1mg£111.00
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TAR-T6610-2mg2mg£130.00
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TAR-T6610-1mL1 mL * 10 mM (in DMSO)£164.00
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TAR-T6610-5mg5mg£168.00
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TAR-T6610-10mg10mg£229.00
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TAR-T6610-25mg25mg£436.00
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Quantity:
TAR-T6610-50mg50mg£610.00
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TAR-T6610-100mg100mg£838.00
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TAR-T6610-500mg500mg£1,613.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
NSC 207895 suppresses MDMX with IC50 of 2.5 μM, leading to enhanced p53 stabilization/activation and DNA damage, and also regulates MDM2, an E3 ligase.
CAS:
58131-57-0
Formula:
C11H13N5O4
Molecular Weight:
279.256
Pathway:
Apoptosis
Purity:
0.9912
SMILES:
CN1CCN(CC1)c1ccc([N+]([O-])=O)c2no[n+]([O-])c12
Target:
Mdm2; p53

References

Kapitzky L, et al. Mol Syst Biol, 2010, 6, 451. Wang H, et al. Mol Cancer Ther, 2011, 10(1), 69-79. Hawes JJ, et al. J Biomol Screen, 2008, 13(8), 795-803. Kessel D, et al. Cancer Res, 1975, 35(12), 3735-3740.