Elaiophylin

Product Code: TAR-T6769

Product Group: Inhibitors and Activators

Supplier: TargetMol

Code	Size	Price

TAR-T6769-1mg

1mg

£204.00

Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.

Quantity:

TAR-T6769-5mg

5mg

£463.00

Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.

Quantity:

TAR-T6769-1mL

1 mL * 10 mM (in DMSO)

£503.00

Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.

Quantity:

Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO

Shipping:

cool pack

Storage:

-20℃

Images

1 / 1

❮❯

Documents

Further Information

Bioactivity:

Elaiophylin shows antiprotozoal activity against Plasmodium falciparum K1a and Trypanosoma brucei brucei GUTat 3.1 strains with IC50 of 0.36 μM and 0.45 μM, respectively.

CAS:

37318-06-2

Formula:

C54H88O18

Molecular Weight:

1025.27

Pathway:

; Autophagy

Purity:

0.98

SMILES:

CC[C@H]1[C@@H](C[C@](O[C@@H]1C)(O)[C@H]([C@H](O)[C@@H]([C@H]2OC(=O)/C=C/C=C/[C@@H]([C@H](OC(=O)/C=C/C=C/[C@@H]2C)[C@H]([C@@H](O)[C@@H]([C@@]3(O[C@@H]([C@H]([C@@H](C3)O[C@@H]4O[C@H]([C@H]([C@H](C4)O)O)C)CC)C)O)C)C)C)C)C)O[C@@H]5O[C@H]([C@H]([C@H](C5)O)O)C

Target:

Autophagy

References

Otoguro K, et al. J Antibiot (Tokyo). 2010, 63(5), 275-277. Liu CM, et al. J Antibiot (Tokyo). 1993, 46(2), 350-352. Zhao X, et al Elaiophylin, a novel autophagy inhibitor, exerts antitumor activity as a single agent in ovarian cancer cells. Autophagy. 2015;11(10):1849-63. Dr?se S, et al. Biochemistry. 1993, 32(15), 3902-3906. Ritzau M, et al. J Nat Prod. 1998, 61(11), 1337-1339. Hammann P, et al. J Antibiot (Tokyo). 1990, 43(11), 1431-1440.