BI-847325

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TargetMol
Product Code: TAR-T6785
Supplier: TargetMol
CodeSizePrice
TAR-T6785-1mg1mg£107.00
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TAR-T6785-2mg2mg£115.00
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TAR-T6785-5mg5mg£152.00
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TAR-T6785-1mL1 mL * 10 mM (in DMSO)£157.00
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TAR-T6785-10mg10mg£213.00
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TAR-T6785-25mg25mg£357.00
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TAR-T6785-50mg50mg£499.00
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TAR-T6785-100mg100mg£688.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
BI-847325 is a selective dual inhibitor of MEK and aurora kinases (AK) with IC50 values of 4 and 15 nM for human MEK2 and AK-C, respectively.
CAS:
1207293-36-4
Formula:
C29H28N4O2
Molecular Weight:
464.569
Pathway:
Cell Cycle/Checkpoint; Chromatin/Epigenetic; Apoptosis; MAPK
Purity:
0.9754
SMILES:
CCNC(=O)C#Cc1ccc2C(=C(Nc3ccc(CN(C)C)cc3)c3ccccc3)C(=O)Nc2c1
Target:
Apoptosis; MEK; Aurora Kinase

References

Phadke MS, et al. Mol Cancer Ther. 2015, 14(6), 1354-1364.