BMS582949

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TargetMol
Product Code: TAR-T6789
Supplier: TargetMol
CodeSizePrice
TAR-T6789-1mg1mg£134.00
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TAR-T6789-2mg2mg£169.00
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TAR-T6789-1mL1 mL * 10 mM (in DMSO)£249.00
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TAR-T6789-5mg5mg£249.00
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TAR-T6789-10mg10mg£324.00
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TAR-T6789-25mg25mg£495.00
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TAR-T6789-50mg50mg£687.00
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TAR-T6789-100mg100mg£938.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
BMS-582949 is a potent and selective p38 mitogen-activated protein kinase (p38 MAPK) inhibitor with IC50 of 13 nM, inhibiting both p38 kinase activity and activation of p38.
CAS:
623152-17-0
Formula:
C22H26N6O2
Molecular Weight:
406.49
Pathway:
MAPK
Purity:
0.9771
SMILES:
CCCNC(=O)c1cn2ncnc(Nc3cc(ccc3C)C(=O)NC3CC3)c2c1C
Target:
p38 MAPK

References

Liu C, et al. J Med Chem. 2010, 53(18):6629-6639. Chen J, Lei C, Nie D, et al.Inorganic arsenic exposure promotes malignant progression by HDAC6?mediated down?regulation of HTRA1.Journal of Applied Toxicology.2023