Chetomin
Code | Size | Price |
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TAR-T6804-1mg | 1mg | £149.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6804-2mg | 2mg | £211.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6804-5mg | 5mg | £324.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6804-10mg | 10mg | £477.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Chetomin is an inhibitor of HIF-1 by weaken transcription of HIF-1, disrupting the binding of HIF-1α and HIF-2α to p300 at low nanomolar concentrations.
CAS:
1403-36-7
Formula:
C31H30N6O6S4
Molecular Weight:
710.86
Pathway:
Cytoskeletal Signaling; Chromatin/Epigenetic; Metabolism; Apoptosis; Angiogenesis
Purity:
0.98
SMILES:
CN1C(=O)[C@@]23C[C@]4([C@H](Nc5ccccc45)N2C(=O)[C@]1(CO)SS3)n1cc(C[C@]23SS[C@](CO)(N(C)C2=O)C(=O)N3C)c2ccccc12
Target:
Apoptosis; HSP; HIF
References
Thomas G Smith, et al. Br J Haematol. 2008, 141(3):325?334.
Staab A,et al. BMC Cancer. 2007, 7:231.
Lu H, et al. FEBS J. 2009, 276(24):7291-7304.
Thomas G Smith, et al. BMC Cancer. 2010, 10:605.
Wu Q, et al. Nanoscale. 2014, 6(20):11940-11952.