Marimastat

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TargetMol
Product Code: TAR-T6885
Supplier: TargetMol
CodeSizePrice
TAR-T6885-1mg1mg£114.00
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TAR-T6885-1mL1 mL * 10 mM (in DMSO)£119.00
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TAR-T6885-5mg5mg£139.00
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Quantity:
TAR-T6885-10mg10mg£174.00
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TAR-T6885-25mg25mg£254.00
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TAR-T6885-50mg50mg£377.00
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TAR-T6885-100mg100mg£522.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Marimastat (BB-2516) is a potent, broad spectrum matrix metalloprotease (MMP) inhibitor. MMP-9 (IC50=3 nM), MMP-1 (IC50=5 nM), MMP-2 (IC50=6 nM), MMP-14 (IC50=9 nM)and MMP-7 (IC50=13 nM).
CAS:
154039-60-8
Formula:
C15H29N3O5
Molecular Weight:
331.413
Pathway:
Proteases/Proteasome
Purity:
0.9811
SMILES:
CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](O)C(=O)NO)C(C)(C)C
Target:
MMP

References

auf dem Keller U, et al. Cancer Res. 2010, 70(19), 7562-7569. Maekawa K, et al. Clin Exp Metastasis. 2002, 19(6), 513-518. Sinno M, et al. Stem Cells Dev. 2013, 22(3), 345-358. Rasmussen HS, et al. Pharmacol Ther. 1997, 75(1), 69-75. Ulasov I, et al. Cancer Med.2013, 2(4), 457-467.