Motolimod

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TargetMol
Product Code: TAR-T6898
Supplier: TargetMol
CodeSizePrice
TAR-T6898-1mg1mg£111.00
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TAR-T6898-2mg2mg£129.00
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TAR-T6898-5mg5mg£168.00
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TAR-T6898-1mL1 mL * 10 mM (in DMSO)£179.00
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TAR-T6898-10mg10mg£229.00
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TAR-T6898-25mg25mg£389.00
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TAR-T6898-50mg50mg£546.00
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TAR-T6898-100mg100mg£749.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
Motolimod (VTX-2337) is an effective and specific Toll-like receptor (TLR) 8 agonist (EC50: 100 nM), > 50-fold selectivity over TLR7.
CAS:
926927-61-9
Formula:
C28H34N4O2
Molecular Weight:
458.606
Pathway:
Immunology/Inflammation
Purity:
0.9927
SMILES:
CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)-c1ccc(cc1)C(=O)N1CCCC1
Target:
TLR

References

Yang W, Sun X, Liu S, et al.TLR8 agonist Motolimod-induced inflammatory death for treatment of acute myeloid leukemia.Biomedicine & Pharmacotherapy.2023, 163: 114759. Monk BJ, et al. J Clin Oncol 31, 2013 (suppl; abstr 3077). Lu H, et al. Clin Cancer Res. 2012, 18(2), 499-509.