Pamapimod

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TargetMol
Product Code: TAR-T6927
Supplier: TargetMol
CodeSizePrice
TAR-T6927-1mg1mg£179.00
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TAR-T6927-5mg5mg£303.00
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TAR-T6927-1mL1 mL * 10 mM (in DMSO)£326.00
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TAR-T6927-10mg10mg£470.00
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TAR-T6927-25mg25mg£707.00
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TAR-T6927-50mg50mg£978.00
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TAR-T6927-100mg100mg£1,291.00
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TAR-T6927-500mg500mg£2,456.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Pamapimod (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase. It inhibits p38α and p38β enzymatic activity with IC50 values of 0.014?0.002 and 0.48? 0.04 microM, respectively with no activity against p38delta or p38 gamma isoforms.
CAS:
449811-01-2
Formula:
C19H20F2N4O4
Molecular Weight:
406.39
Pathway:
MAPK; Autophagy
Purity:
0.9999
SMILES:
Cn1c2nc(NC(CCO)CCO)ncc2cc(Oc2ccc(F)cc2F)c1=O
Target:
p38 MAPK; Autophagy

References

Hill RJ, et al. J Pharmacol Exp Ther. 2008, 327(3):610-9.