PRX-08066 Maleic acid
Code | Size | Price |
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TAR-T6959-5mg | 5mg | £215.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6959-10mg | 10mg | £267.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6959-1mL | 1 mL * 10 mM (in DMSO) | £410.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6959-25mg | 25mg | £426.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
PRX-08066 Maleic acid is a selective 5-HT2B receptor antagonist with IC50 of 3.4 nM, prevents the severity of pulmonary arterial hypertension in the MCT rat model. Phase 2.
CAS:
866206-55-5
Formula:
C23H21ClFN5O4S
Molecular Weight:
517.96
Pathway:
GPCR/G Protein; Neuroscience
Purity:
0.98
SMILES:
OC(=O)C=C/C(O)=O.Fc1ccc(CN2CCC(CC2)Nc2ncnc3sc(Cl)cc23)cc1C#N
Target:
5-HT Receptor
References
Porvasnik SL, et al. J Pharmacol Exp Ther, 2010, 334(2), 364-372.
Svejda B, et al. Cancer, 2010, 116(12), 2902-2912.