RK33

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TargetMol
Product Code: TAR-T6970
Supplier: TargetMol
CodeSizePrice
TAR-T6970-1mg1mg£114.00
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TAR-T6970-2mg2mg£123.00
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TAR-T6970-1mL1 mL * 10 mM (in DMSO)£165.00
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Quantity:
TAR-T6970-5mg5mg£165.00
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Quantity:
TAR-T6970-10mg10mg£222.00
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Quantity:
TAR-T6970-25mg25mg£389.00
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TAR-T6970-50mg50mg£544.00
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TAR-T6970-100mg100mg£744.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
RK-33 is a first-in-class small molecule inhibitor of DDX3 (a RNA helicase) and causes G1 cell cycle arrest, induces apoptosis, and promotes radiation sensitization in DDX3-overexpressing cells.
CAS:
1070773-09-9
Formula:
C23H20N6O3
Molecular Weight:
428.452
Pathway:
Neuroscience; Immunology/Inflammation
Purity:
0.9755
SMILES:
COc1ccc(Cn2cnc3c4nc(=O)n(Cc5ccc(OC)cc5)c4ncnc23)cc1
Target:
COX

References

Bol GM, et al. EMBO Mol Med. 2015, 7(5):648-69.