BAY-598
Code | Size | Price |
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TAR-T7403-1mg | 1mg | £112.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T7403-5mg | 5mg | £156.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T7403-1mL | 1 mL * 10 mM (in DMSO) | £169.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T7403-10mg | 10mg | £206.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T7403-25mg | 25mg | £282.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T7403-50mg | 50mg | £429.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T7403-100mg | 100mg | £648.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
BAY-598 is a selective inhibitor of SMYD2 with IC50 values of 27 nM.
CAS:
1906919-67-2
Formula:
C22H20Cl2F2N6O3
Molecular Weight:
525.34
Pathway:
Chromatin/Epigenetic
Purity:
0.9918
SMILES:
CCN(C1CN(N=C1c1ccc(Cl)c(Cl)c1)C(NC#N)=Nc1cccc(OC(F)F)c1)C(=O)CO
Target:
Histone Methyltransferase
References
Reynoird N , Mazur P K , Stellfeld T , et al. Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer[J]. Genes & Development, 2016:genesdev;gad.275529.115v1.
Eggert E , Hillig R C , K?Hr S , et al. Discovery and Characterization of a Highly Potent and Selective Aminopyrazoline-Based in vivo Probe (BAY-598) for the Protein Lysine Methyltransferase SMYD2[J]. Journal of Medicinal Chemistry, 2016:acs.jmedchem.5b01890.