ARS-1620

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TargetMol
Product Code: TAR-T7609
Supplier: TargetMol
CodeSizePrice
TAR-T7609-1mg1mg£138.00
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TAR-T7609-5mg5mg£230.00
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TAR-T7609-1mL1 mL * 10 mM (in DMSO)£250.00
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TAR-T7609-10mg10mg£303.00
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TAR-T7609-25mg25mg£530.00
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TAR-T7609-50mg50mg£731.00
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TAR-T7609-100mg100mg£863.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
ARS-1620 is a covalent inhibitor of K-RASG12C.
CAS:
1698055-85-4
Formula:
C21H17ClF2N4O2
Molecular Weight:
430.84
Pathway:
MAPK; GPCR/G Protein
Purity:
0.98
SMILES:
C=CC(=O)N1CCN(c2ncnc3c(F)c(-c4c(O)cccc4F)c(Cl)cc23)CC1
Target:
Ras

References

Janes M R , Zhang J , Li L S , et al. Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor[J]. Cell, 2018, 172(3):578-589.e17.