AZD-5069

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TargetMol
Product Code: TAR-T7681
Supplier: TargetMol
CodeSizePrice
TAR-T7681-1mg1mg£107.00
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TAR-T7681-2mg2mg£118.00
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TAR-T7681-5mg5mg£132.00
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TAR-T7681-1mL1 mL * 10 mM (in DMSO)£135.00
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TAR-T7681-10mg10mg£172.00
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TAR-T7681-25mg25mg£262.00
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TAR-T7681-50mg50mg£367.00
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TAR-T7681-100mg100mg£511.00
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TAR-T7681-500mg500mg£1,026.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
AZD-5069 is an chemokine receptor 2 antagonist (CXCR2; IC50 = 0.79 nM).
CAS:
878385-84-3
Formula:
C18H22F2N4O5S2
Molecular Weight:
476.51
Pathway:
GPCR/G Protein; Immunology/Inflammation; Autophagy
Purity:
0.9885
SMILES:
CC(Oc1cc(NS(=O)(=O)N2CCC2)nc(SCc2cccc(F)c2F)n1)C(O)CO
Target:
CXCR

References

Nicholls D J , Wiley K , Dainty I , et al. Pharmacological Characterization of AZD5069, a Slowly Reversible CXC Chemokine Receptor 2 Antagonist[J]. Journal of Pharmacology and Experimental Therapeutics, 2015, 353(2):340-350. Norman, Peter. Evidence on the identity of the CXCR2 antagonist AZD-5069[J]. Expert Opinion on Therapeutic Patents, 2013, 23(1):113-117.