TBK1/IKKε-IN-5

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TargetMol
Product Code: TAR-T7951
Supplier: TargetMol
CodeSizePrice
TAR-T7951-1mg1mg£198.00
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TAR-T7951-5mg5mg£343.00
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TAR-T7951-1mL1 mL * 10 mM (in DMSO)£418.00
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TAR-T7951-10mg10mg£507.00
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TAR-T7951-25mg25mg£776.00
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TAR-T7951-50mg50mg£1,026.00
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Quantity:
TAR-T7951-100mg100mg£1,380.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
TBK1/IKKε-IN-5 is a dual TBK1 and IKKε inhibitor(IC50 of 1 nM and 5.6 nM, respectively).
CAS:
1893397-65-3
Formula:
C28H31N7O3
Molecular Weight:
513.602
Pathway:
NF-κb
Purity:
0.9993
SMILES:
N#Cc1cc(ccc1OC1CCOCC1)-c1ncnc(Nc2ccc(cc2)N2CCN(CC2)C2COC2)n1
Target:
IκB/IKK

References

Jenkins RW, et al. Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids. Cancer Discov. 2018 Feb;8(2):196-215.