SX-682

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TargetMol
Product Code: TAR-T8497
Supplier: TargetMol
CodeSizePrice
TAR-T8497-1mg1mg£98.00
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TAR-T8497-5mg5mg£135.00
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TAR-T8497-1mL1 mL * 10 mM (in DMSO)£142.00
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TAR-T8497-10mg10mg£168.00
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TAR-T8497-25mg25mg£254.00
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TAR-T8497-50mg50mg£374.00
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TAR-T8497-100mg100mg£527.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
SX-682 is a potent, selective and orally bioavailable inhibitor of CXCR1/2 ,has the potential to treat castration-resistant prostate cancer.
CAS:
1648843-04-2
Formula:
C19H14BF4N3O4S
Molecular Weight:
467.2
Pathway:
GPCR/G Protein; Immunology/Inflammation; Autophagy
Purity:
0.9957
SMILES:
OB(O)c1ccc(OC(F)(F)F)cc1CSc1ncc(cn1)C(=O)Nc1ccc(F)cc1
Target:
CXCR

References

Lu X, et al. Effective combinatorial immunotherapy for castration-resistant prostate cancer. Nature. 2017 Mar 30;543(7647):728-732. Sun L , Clavijo P E , Robbins Y , et al. Inhibiting myeloid-derived suppressor cell trafficking enhances T cell immunotherapy[J]. 2019.