K-Ras-PDEδ-IN-1

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TargetMol
Product Code: TAR-T8659
Supplier: TargetMol
CodeSizePrice
TAR-T8659-1mg1mg£135.00
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TAR-T8659-5mg5mg£229.00
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TAR-T8659-1mL1 mL * 10 mM (in DMSO)£245.00
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TAR-T8659-10mg10mg£328.00
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TAR-T8659-25mg25mg£542.00
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TAR-T8659-50mg50mg£744.00
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TAR-T8659-100mg100mg£1,002.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
K-Ras-PDEδ-IN-1 is a potent inhibitor of competitive K-Ras-PDEδ.It binds to the farnesyl binding pocket of PDEδ(Kd of 8 nM).
CAS:
1841464-21-8
Formula:
C25H26FN5O2
Molecular Weight:
447.514
Pathway:
Metabolism
Purity:
0.9974
SMILES:
Cc1ccc(cc1)-n1cc2c(C)nn(CCCC(=O)NCCc3ccc(F)cc3)c(=O)c2n1
Target:
PDE

References

Sandip Murarka, et al. Development of Pyridazinone Chemotypes Targeting the PDE? Prenyl Binding Site. Chemistry. 2017 May 2;23(25):6083-6093.