HA-1004 dihydrochloride
| Code | Size | Price |
|---|
| TAR-T8681-1mg | 1mg | £368.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
HA-1004 dihydrochloride is an inhibitor of PKA, PKC, cGKI, MYLK, and calcium channel protein
CAS:
92564-34-6
Formula:
C12H16ClN5O2S
Molecular Weight:
329.8
Pathway:
Cytoskeletal Signaling; Metabolism; Chromatin/Epigenetic; Membrane transporter/Ion channel; Tyrosine Kinase/Adaptors
Purity:
0.98
SMILES:
Cl.NC(N)=NCCNS(=O)(=O)c1cccc2cnccc12
Target:
Calcium Channel; PKA; PKC
References
Ishikawa T , Inagaki M , Watanabe M , et al. Relaxation of vascular smooth muscle by HA-1004, an inhibitor of cyclic nucleotide-dependent protein kinase[J]. Journal of Pharmacology and Experimental Therapeutics, 1985, 235(2):495-499.
Maurice G H , Ruey T L , Chipkin S R . The isoquinoline sulfonamide inhibitors of protein phosphorylation, H-7, H-8, and HA-1004, also inhibit RNA synthesis: studies on responses of adipose tissue to growth hormone.[J]. Endocrinology, 1990(1):441.