TargetMol

BAR 501 impurity

Product Code:
 
TAR-T8752
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8752-1mg1mg£177.00
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TAR-T8752-5mg5mg£313.00
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TAR-T8752-1mL1 mL * 10 mM (in DMSO)£346.00
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TAR-T8752-10mg10mg£434.00
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TAR-T8752-25mg25mg£670.00
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TAR-T8752-50mg50mg£914.00
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Quantity:
TAR-T8752-100mg100mg£1,211.00
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This product comes from: United States.
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Further Information

Bioactivity:
BAR501 impurity is an impurity found in the preparation of BAR501 that acts as an agonist of the G protein-coupled bile acid-activated receptor (GP-BAR1). BAR501 impurity (10 μM) induces a 150% increase in luciferase activity in a GP-BAR1 reporter gene assay
CAS:
1632118-70-7
Formula:
C26H46O3
Molecular Weight:
406.651
Pathway:
GPCR/G Protein
Purity:
0.9997
SMILES:
[H][C@@]12CC[C@H]([C@H](C)CCCO)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])[C@H](O)[C@@H](CC)[C@]2([H])C[C@H](O)CC[C@]12C
Target:
GPCR19

References

Renga B, et al. Reversal of Endothelial Dysfunction by GPBAR1 Agonism in Portal Hypertension Involves a AKT/FOXOA1 Dependent Regulation of H2S Generation and Endothelin-1.