ICCB280

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TargetMol
Product Code: TAR-T8839
Supplier: TargetMol
CodeSizePrice
TAR-T8839-1mg1mg£130.00
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TAR-T8839-2mg2mg£157.00
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TAR-T8839-5mg5mg£213.00
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TAR-T8839-1mL1 mL * 10 mM (in DMSO)£229.00
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TAR-T8839-10mg10mg£329.00
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TAR-T8839-25mg25mg£490.00
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TAR-T8839-50mg50mg£680.00
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TAR-T8839-100mg100mg£922.00
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TAR-T8839-500mg500mg£1,781.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
ICCB280 was capable of inducing differentiation and apoptosis of ATRA-resistant patient blasts strongly signify that the activity of this compound can overcome resistance to other current therapies for AML with an unfavorable prognosis.
CAS:
2041072-41-5
Formula:
C23H18N2O4
Molecular Weight:
386.407
Pathway:
Apoptosis;
Purity:
0.9896
SMILES:
COc1ccccc1-n1c(C=Cc2ccc(O)c(O)c2)nc2ccccc2c1=O
Target:
Apoptosis;

References

Radomska HS, Jernigan F, Nakayama S, et al. A Cell-Based High-Throughput Screening for Inducers of Myeloid Differentiation. J Biomol Screen. 2015;20(9):1150-1159. doi:10.1177/1087057115592220