TM5007
Code | Size | Price |
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TAR-T8962-1mg | 1mg | £189.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T8962-5mg | 5mg | £314.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T8962-10mg | 10mg | £437.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T8962-25mg | 25mg | £672.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T8962-50mg | 50mg | £922.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
TM5007 is a poent inhibitor of plasminogen activator inhibitor-1 (PAI-1; IC50 of 29 uM).
CAS:
342595-05-5
Formula:
C24H20N2O6S4
Molecular Weight:
560.67
Pathway:
Metabolism
Purity:
0.9691
SMILES:
OC(=O)c1c(NC(=O)CCCCC(=O)Nc2scc(-c3cccs3)c2C(O)=O)scc1-c1cccs1
Target:
PAI-1
References
Izuhara Y , Takahashi S , Nangaku M , et al. Inhibition of Plasminogen Activator Inhibitor-1 Its Mechanism and Effectiveness on Coagulation and Fibrosis[J]. Arteriosclerosis Thrombosis and Vascular Biology, 2008, 28(4):672-677.
Izuhara Y , Yamaoka N , Kodama H , et al. A novel inhibitor of plasminogen activator inhibitor-1 provides antithrombotic benefits devoid of bleeding effect in nonhuman primates[J]. Journal of Cerebral Blood Flow & Metabolism Official Journal of the International Society of Cerebral Blood Flow & Metabolism, 2010, 30(5):904.