KY19382

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TargetMol
Product Code: TAR-T9025
Supplier: TargetMol
CodeSizePrice
TAR-T9025-1mg1mg£151.00
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TAR-T9025-5mg5mg£237.00
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TAR-T9025-1mL1 mL * 10 mM (in DMSO)£275.00
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Quantity:
TAR-T9025-10mg10mg£367.00
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Quantity:
TAR-T9025-25mg25mg£570.00
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TAR-T9025-50mg50mg£781.00
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Quantity:
TAR-T9025-100mg100mg£1,026.00
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TAR-T9025-500mg500mg£2,022.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
KY19382 is a potent and orally active dual inhibitor of CXXC5-DVL and GSK3β( IC50s of 19 and 10 nM, respectively). It activates Wnt/β-catenin signaling through inhibitory effects on both CXXC5-DVL interaction and GSK3β activity. KY19382 can be used for the research of high fat diet (HFD) induced metabolic diseases.
CAS:
2226664-93-1
Formula:
C17H11Cl2N3O2
Molecular Weight:
360.19
Pathway:
Cytoskeletal Signaling; ; Stem Cells; PI3K/Akt/mTOR signaling
Purity:
0.9806
SMILES:
CON=C1/C(=Nc2ccccc12)c1c(O)[nH]c2cc(Cl)c(Cl)cc12
Target:
GSK-3; Wnt/beta-catenin