IU1-248

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TargetMol
Product Code: TAR-T9375
Supplier: TargetMol
CodeSizePrice
TAR-T9375-1mg1mg£127.00
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TAR-T9375-5mg5mg£209.00
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TAR-T9375-1mL1 mL * 10 mM (in DMSO)£222.00
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TAR-T9375-10mg10mg£294.00
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TAR-T9375-25mg25mg£523.00
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TAR-T9375-50mg50mg£707.00
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TAR-T9375-100mg100mg£978.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
IU1-248 is a derivative of IU1. IU1-248 is a potent and selective USP14 inhibitor with an IC50 of 0.83?μM[1].
CAS:
2307472-03-1
Formula:
C20H23N3O2
Molecular Weight:
337.42
Pathway:
Ubiquitination; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Purity:
0.9849
SMILES:
Cc1cc(C(CN(CC2)CCC2O)=O)c(C)n1-c(cc1)ccc1C#N
Target:
DUB

References

Yiwei Wang, et al. Small molecule inhibitors reveal allosteric regulation of USP14 via steric blockade. Cell Res. 2018 Dec;28(12):1186-1194.