Compound 1T-0219 (SC)
Code | Size | Price |
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TAR-T9545-1mg | 1mg | £189.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T9545-5mg | 5mg | £340.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T9545-10mg | 10mg | £470.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T9545-25mg | 25mg | £707.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T9545-50mg | 50mg | £978.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Compound 1T-0219 (SC) is a blocker of AKT1-FAK interaction reducing the stimulation of FAK phosphorylation in response to extracellular pressure in human SW620 colon cancer cells without affecting basal FAK phosphorylation.
CAS:
383147-92-0
Formula:
C20H19N3O7
Molecular Weight:
413.386
Pathway:
Cytoskeletal Signaling; Angiogenesis; Tyrosine Kinase/Adaptors
Purity:
0.98
SMILES:
COc1ccc(cc1)C(=O)ON=C1/CCCCC1c1ccc(cc1[N+]([O-])=O)[N+]([O-])=O
Target:
FAK
References
More SK, Vomhof-Dekrey EE, Basson MD. ZINC4085554 inhibits cancer cell adhesion by interfering with the interaction of Akt1 and FAK. Oncol Lett. 2019 Jun;17(6):5251-5260. doi: 10.3892/ol.2019.10192. Epub 2019 Mar 27. PMID: 31186741; PMCID: PMC6507311.