Tepotinib hydrochloride(1 : x)
Code | Size | Price |
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TAR-T9601-1mg | 1mg | £189.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Quantity:
TAR-T9601-5mg | 5mg | £340.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Quantity:
TAR-T9601-1mL | 1 mL * 10 mM (in DMSO) | £410.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Quantity:
TAR-T9601-10mg | 10mg | £470.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Quantity:
TAR-T9601-25mg | 25mg | £707.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Quantity:
TAR-T9601-50mg | 50mg | £978.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Tepotinib hydrochloride(1 : x) is an orally bioavailable, mesenchymal-epithelial transition (MET) TKI developed mainly for selected NSCLC patients with METex14 skipping mutations.
CAS:
1103508-80-0
Formula:
C29H29ClN6O2
Molecular Weight:
529.04
Pathway:
Neuroscience; Tyrosine Kinase/Adaptors; Membrane transporter/Ion channel
Purity:
0.98
SMILES:
0
Target:
c-Met/HGFR; P-gp; ABC
References
Vagiannis D, et al. Tepotinib Inhibits Several Drug Efflux Transporters and Biotransformation Enzymes: The Role in Drug-Drug Interactions and Targeting Cytostatic Resistance In Vitro and Ex Vivo. Int J Mol Sci. 2021 Nov 3;22(21):11936.
Wu ZX, et al. Tepotinib hydrochloride for the treatment of non-small cell lung cancer. Drugs Today (Barc). 2021 Apr;57(4):265-275.