SIRT1-IN-1

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TargetMol
Product Code: TAR-T9648
Supplier: TargetMol
CodeSizePrice
TAR-T9648-1mg1mg£201.00
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Quantity:
TAR-T9648-1mL1 mL * 10 mM (in DMSO)£362.00
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Quantity:
TAR-T9648-5mg5mg£402.00
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Quantity:
TAR-T9648-10mg10mg£567.00
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Quantity:
TAR-T9648-25mg25mg£862.00
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Quantity:
TAR-T9648-50mg50mg£1,139.00
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Quantity:
TAR-T9648-100mg100mg£1,508.00
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Quantity:
TAR-T9648-500mg500mg£2,954.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
SIRT1-IN-1 is a selective inhibitor of SIRT1 with an IC50 of 205 nM. SIRT1-IN-1 is an inhibitor of cytomegalovirus (CMV) with antiviral activity.
CAS:
352554-02-0
Formula:
C14H16N2O
Molecular Weight:
228.29
Pathway:
Chromatin/Epigenetic; Immunology/Inflammation; DNA Damage/DNA Repair
Purity:
0.9931
SMILES:
O=C(N)C1C=2NC=3C=CC(=CC3C2CCC1)C
Target:
Antiviral; Sirtuin

References

Andrew D Napper, et al. Discovery of Indoles as Potent and Selective Inhibitors of the Deacetylase SIRT1. J Med Chem. 2005 Dec 15;48(25):8045-54. Thomas Shenk, et al. Sirtuin Modulators as Inhibitors of Cytomegalovirus. US20160296523A1.