TBAP-001

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TargetMol
Product Code: TAR-T9693
Supplier: TargetMol
CodeSizePrice
TAR-T9693-1mg1mg£140.00
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TAR-T9693-5mg5mg£242.00
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TAR-T9693-1mL1 mL * 10 mM (in DMSO)£270.00
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TAR-T9693-10mg10mg£346.00
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Quantity:
TAR-T9693-25mg25mg£539.00
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Quantity:
TAR-T9693-50mg50mg£741.00
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Quantity:
TAR-T9693-100mg100mg£994.00
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TAR-T9693-500mg500mg£1,910.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
TBAP-001 is a RAF kinase inhibitor, with an IC50 of 62 nM in BRAF V600E kinase assay and an IC50 of 18 nM in Cell-Based Phosho-ERK Assay.
CAS:
1777832-90-2
Formula:
C27H23F2N7O3
Molecular Weight:
531.51
Pathway:
MAPK
Purity:
0.993
SMILES:
CC(C)(C)c(cc1NC(Nc(ccc(Oc(ccnc2N3)c2N=CC3=O)c2)c2F)=O)nn1-c1cc(F)ccc1
Target:
Raf

References

Caroline Joy, et al. 1 -(5-TERT-BUTYL-2-ARYL-PYRAZOL-3-YL)-3-[2-FLUORO-4-[(3-OXO-4H-PYRIDO[2, 3-B]PYRAZIN-8-YL)OXY]PHENYL]UREA DERIVATIVES AS RAF INHIBITORS FOR THE TREATMENT OF CANCER.WO2015075483A1