TargetMol

ART-CHEM-BB B025267

Product Code:
 
TAR-T9821
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T9821-1mg1mg£227.00
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TAR-T9821-1mL1 mL * 10 mM (in DMSO)£405.00
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TAR-T9821-5mg5mg£422.00
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TAR-T9821-10mg10mg£589.00
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TAR-T9821-25mg25mg£863.00
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Quantity:
TAR-T9821-50mg50mg£1,179.00
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Quantity:
TAR-T9821-100mg100mg£1,564.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
ART-CHEM-BB B025267 is the upregulator of utrophin production with EC50 of 1.8 μM and can be used in research on the treatment of Duchenne muscular dystrophy.
CAS:
381208-40-8
Formula:
C17H21N5
Molecular Weight:
295.38
Purity:
0.98
SMILES:
CCN(CC)c(cc1)ccc1-n1nc(cc(c(C)c2)N)c2n1

References

De Moor O, et al. Discovery and SAR of 2-arylbenzotriazoles and 2-arylindazoles as potential treatments for Duchenne muscular dystrophy. Bioorg Med Chem Lett. 2011 Aug 15;21(16):4828-31. Chancellor DR, et al. Discovery of 2-arylbenzoxazoles as upregulators of utrophin production for the treatment of Duchenne muscular dystrophy. J Med Chem. 2011 May 12;54(9):3241-50.