Avelumab

TargetMol
Product Code: TAR-T9903
Product Group: Primary Antibodies
Supplier: TargetMol
CodeSizePrice
TAR-T9903-1mg1mg£303.00
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TAR-T9903-5mg5mg£630.00
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TAR-T9903-10mg10mg£863.00
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TAR-T9903-25mg25mg£1,267.00
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Quantity:
TAR-T9903-50mg50mg£1,661.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Antibody Clonality: Monoclonal
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Avelumab is a fully human IgG1 anti-PD-L1 monoclonal antibody. Avelumab shows potential antibody-dependent cell-mediated cytotoxicity.
CAS:
1537032-82-8
Formula:
0
Molecular Weight:
147 kDa
Pathway:
Cell Cycle/Checkpoint; Immunology/Inflammation; Apoptosis
Purity:
0.98
SMILES:
0
Target:
PD-1/PD-L1

References

Fujii R, et al. Enhanced killing of chordoma cells by antibody-dependent cell-mediated cytotoxicity employing the novel anti-PD-L1 antibody avelumab. Oncotarget. 2016 Jun 7;7(23):33498-511. Grenga I, et al. A fully human IgG1 anti-PD-L1 MAb in an in vitro assay enhances antigen-specific T-cell responses. Clin Transl Immunology. 2016 May 20;5(5):e83. Vandeveer AJ, et al. Systemic Immunotherapy of Non-Muscle Invasive Mouse Bladder Cancer with Avelumab, an Anti-PD-L1 Immune Checkpoint Inhibitor. Cancer Immunol Res. 2016 May;4(5):452-62.