Cetuximab

TargetMol
Product Code: TAR-T9905
Product Group: Primary Antibodies
Supplier: TargetMol
CodeSizePrice
TAR-T9905-1mg1mg£229.00
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TAR-T9905-2mg2mg£303.00
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Quantity:
TAR-T9905-5mg5mg£458.00
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Quantity:
TAR-T9905-10mg10mg£630.00
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Quantity:
TAR-T9905-25mg25mg£962.00
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Prices exclude any Taxes / VAT

Overview

Antibody Clonality: Monoclonal
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Cetuximab (anti-EGFR) a novel molecular-targeted agentis an inhibitor of EGFR monoclonal humanized antibody interacting with the extracellular binding site of EGFR to block ligand stimulation.
CAS:
205923-56-4
Formula:
C107H179N35O36S7
Molecular Weight:
152kd
Pathway:
JAK/STAT signaling; Tyrosine Kinase/Adaptors; Angiogenesis
Purity:
0.98
SMILES:
0
Target:
EGFR

References

H, Gustafsso, A, et al. EPR Oximetry of Cetuximab-Treated Head-and-Neck Tumours in a Mouse Model[J]. Cell Biochemistry & Biophysics, 2017. Komatsu M, Nakamura K, Takeda T, et al. Aurora kinase blockade drives de novo addiction of cervical squamous cell carcinoma to druggable EGFR signalling. Oncogene. 2022: 1-14. Huang S M , Bock J M , Harari P M . Epidermal Growth Factor Receptor Blockade with C225 Modulates Proliferation, Apoptosis, and Radiosensitivity in Squamous Cell Carcinomas of the Head and Neck1[J]. Cancer Res, 1999, 59(8):1935-1940.