Trastuzumab

TargetMol
Product Code: TAR-T9912
Product Group: Primary Antibodies
Supplier: TargetMol
CodeSizePrice
TAR-T9912-1mg1mg£198.00
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TAR-T9912-5mg5mg£511.00
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Quantity:
TAR-T9912-10mg10mg£624.00
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Quantity:
TAR-T9912-25mg25mg£870.00
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Prices exclude any Taxes / VAT

Overview

Antibody Clonality: Monoclonal
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2. Trastuzumab has been clinically used to treat HER2 Positive Metastatic Breast Cancer and HER2 Positive Gastric Cancer.
CAS:
180288-69-1
Formula:
0
Molecular Weight:
146 kDa
Pathway:
Tyrosine Kinase/Adaptors; Angiogenesis; JAK/STAT signaling
Purity:
0.98
SMILES:
0
Target:
EGFR

References

Sliwkowski MX, et al. Nonclinical studies addressing the mechanism of action of trastuzumab (Herceptin). Semin Oncol. 1999 Aug;26(4 Suppl 12):60-70. Hudis CA, et al. Trastuzumab--mechanism of action and use in clinical practice. N Engl J Med. 2007 Jul 5;357(1):39-51. Barok M, et al. Trastuzumab causes antibody-dependent cellular cytotoxicity-mediated growth inhibition of submacroscopic JIMT-1 breast cancer xenografts despite intrinsic drug resistance. Mol Cancer Ther. 2007 Jul;6(7):2065-72.