GPR183

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TargetMol

Product Code: TAR-T9975

Product Group: Inhibitors and Activators

Supplier: TargetMol

Code	Size	Price

TAR-T9975-1mg

1mg

£148.00

Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.

Quantity:

TAR-T9975-5mg

5mg

£269.00

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Quantity:

TAR-T9975-1mL

1 mL * 10 mM (in DMSO)

£289.00

Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.

Quantity:

TAR-T9975-10mg

10mg

£389.00

Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.

Quantity:

TAR-T9975-25mg

25mg

£603.00

Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.

Quantity:

TAR-T9975-50mg

50mg

£830.00

Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.

Quantity:

TAR-T9975-100mg

100mg

£1,099.00

Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.

Quantity:

Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO

Shipping:

cool pack

Storage:

-20℃

Images

1 / 1

Documents

Further Information

Bioactivity:

GPR183 is a chemotactic receptor known for its role in the maturation of B cells, and the endogenous ligand is the oxysterol 7α,25-dihydroxycholesterol (7α,25-OHC). GPR183 can be used in research on inflammatory bowel disease (IBD).

CAS:

1241280-25-0

Formula:

C19H19F3N2O2

Molecular Weight:

364.368

Purity:

0.98

SMILES:

Fc1cc(NC(=O)CCc2ccc(F)c(F)c2)cc(c1)N1CCOCC1

References

Misselwitz B, et al. The oxysterol receptor GPR183 in inflammatory bowel diseases. Br J Pharmacol. 2021 Aug;178(16):3140-3156. Braden K, et al. GPR183-Oxysterol Axis in Spinal Cord Contributes to Neuropathic Pain. J Pharmacol Exp Ther. 2020 Nov;375(2):367-375.