TargetMol

Epimagnolin B

Product Code:
 
TAR-TN1009
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN1009-1mg1mg£193.00
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TAR-TN1009-5mg5mg£319.00
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TAR-TN1009-10mg10mg£495.00
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TAR-TN1009-25mg25mg£834.00
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Further Information

Bioactivity:
Epimagnolin B has anti-inflammatory activity, it can inhibit the production of NO and PGE(2) and the expression of respective enzyme iNOS and COX-2 through the suppression of I-kappaB-alpha degradation and nuclear translocation of p65 subunit of NF-kappaB. It also exhibits antiallergic effects without affecting the viability of bone marrow-derived mast cells.
CAS:
1134188-26-3
Formula:
C23H28O7
Molecular Weight:
416.47
Pathway:
NF-κb; GPCR/G Protein; Immunology/Inflammation
Purity:
0.98
SMILES:
[H][C@@]12CO[C@H](c3cc(OC)c(OC)c(OC)c3)[C@]1([H])CO[C@H]2c1cc(OC)cc(OC)c1
Target:
NF-κB; NO Synthase; Prostaglandin Receptor

References

In vitro anti-inflammatory activity of lignans isolated from Magnolia fargesii.Bioorg Med Chem Lett. 2009 Feb 1;19(3):937-40.