TargetMol

(-)-Butin

Product Code:
 
TAR-TN1461
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN1461-1mg1mg£124.00
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TAR-TN1461-5mg5mg£197.00
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TAR-TN1461-10mg10mg£254.00
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Quantity:
TAR-TN1461-1mL1 mL * 10 mM (in DMSO)£336.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
(-)-Butin has antioxidant activity, can protect cells against H2O2-induced apoptosis, oxidative DNA damage and oxidative mitochondrial dysfunction; it attenuates oxidative stress by activating Nrf2-mediated Mn SOD induction via the PI3K/Akt signaling pathway.
CAS:
492-14-8
Formula:
C15H12O5
Molecular Weight:
272.256
Pathway:
Immunology/Inflammation; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
Purity:
0.9807
SMILES:
Oc1ccc2C(=O)C[C@H](Oc2c1)c1ccc(O)c(O)c1
Target:
Akt; PI3K; Nrf2

References

The cytoprotective effect of butin against oxidative stress is mediated by the up-regulation of manganese superoxide dismutase expression through a PI3K/Akt/Nrf2-dependent pathway.J Cell Biochem. 2012 Jun;113(6):1987-97.