TargetMol

Cucurbitacin A

Product Code:
 
TAR-TN1533
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN1533-5mg5mg£392.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-TN1533-1mL1 mL * 10 mM (in DMSO)£560.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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Further Information

Bioactivity:
Cucurbitacin I, cytotoxic triterpenoid sterols isolated from plants, elicits the formation of actin/phospho-myosin II co-aggregates by stimulation of the RhoA/ROCK pathway and inhibition of LIM-Kinase.
CAS:
6040-19-3
Formula:
C32H46O9
Molecular Weight:
574.711
Pathway:
Stem Cells; Cell Cycle/Checkpoint; Cytoskeletal Signaling
Purity:
0.98
SMILES:
[H][C@@]12C[C@H](O)C(=O)C(C)(C)C1=CC[C@@]1([H])[C@]3(C)C[C@@H](O)[C@H]([C@@](C)(O)C(=O)C=CC(C)(C)OC(C)=O)[C@@]3(C)CC(=O)[C@@]21CO
Target:
ROCK

References

Cucurbitacin I elicits the formation of actin/phospho-myosin II co-aggregates by stimulation of the RhoA/ROCK pathway and inhibition of LIM-kinase.Biochem. Pharmacol., 2015, 102:45-63.