Isocryptotanshinone
| Code | Size | Price |
|---|
| TAR-TN1775-5mg | 5mg | £705.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-TN1775-1mL | 1 mL * 10 mM (in DMSO) | £721.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Isocryptotanshinone inhibits protein tyrosine phosphatase 1B (PTP1B) activity with 50% inhibitory concentration values of 56.1?6.3 μM, PTP1B acts as a negative regulator of insulin signaling, and selective inhibition of PTP1B has served as a potential drug target for the treatment of type 2 diabetes.
CAS:
22550-15-8
Formula:
C19H20O3
Molecular Weight:
296.366
Pathway:
MAPK; Stem Cells; JAK/STAT signaling
Purity:
0.98
SMILES:
C[C@@H]1COC2=C1C(=O)c1ccc3c(CCCC3(C)C)c1C2=O
Target:
ERK; JNK; STAT
References
Isocryptotanshinone Induced Apoptosis and Activated MAPK Signaling in Human Breast Cancer MCF-7 Cells.J Breast Cancer. 2015 Jun; 18(2): 112??118.