Kanzonol C

TargetMol
Product Code: TAR-TN1832
Supplier: TargetMol
CodeSizePrice
TAR-TN1832-5mg5mg£303.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-TN1832-1mL1 mL * 10 mM (in DMSO)£311.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Kanzonol C has antimicrobial activity, it also shows potent PTP1B inhibitory activity (IC50 value of 0.31-0.97uM). Kanzonol C has chemopreventive activity,it shows the inhibition of matrix metalloproteinase (MMP)-2 secretion from brain tumor-derived glioblastoma cells.
CAS:
151135-82-9
Formula:
C25H28O4
Molecular Weight:
392.495
Pathway:
NF-κb; Proteases/Proteasome;
Purity:
0.98
SMILES:
CC(C)=CCc1cc(C=CC(=O)c2ccc(O)c(CC=C(C)C)c2O)ccc1O
Target:
NF-κB; Tyrosinase

References

Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata.Bioorg Med Chem. 2017 Jul 15;25(14):3706-3713.