TargetMol

Kobusin

Product Code:
 
TAR-TN1834
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN1834-5mg5mg£183.00
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Quantity:
TAR-TN1834-1mL1 mL * 10 mM (in DMSO)£199.00
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Further Information

Bioactivity:
Kobusin, a Calmodulin inhibitor, shows mild antiplasmodial,anti-inflammatory, and cytotoxic activities; it may be beneficial for the treatment of neuro-inflammatory diseases through the inhibition of iNOS expression and peroxynitrite scavenging potential. Kobusin can mildly reduce gastrointestinal motility in mice, it activates CFTR and CaCCgie chloride channel activities in mouse colonic epithelia and shows inhibitory effects toward ANO1/CaCC-mediated short-circuit currents in ANO1/CaCC-expressing FRT cells.
CAS:
36150-23-9
Formula:
C21H22O6
Molecular Weight:
370.401
Pathway:
NF-κb; Immunology/Inflammation;
Purity:
0.98
SMILES:
COc1ccc(cc1OC)[C@H]1OC[C@H]2[C@H]1CO[C@@H]2c1ccc2OCOc2c1
Target:
NOS; NF-κB

References

Bioactive Constituents of Zanthoxylum rhetsa Bark and Its Cytotoxic Potential against B16-F10 Melanoma Cancer and Normal Human Dermal Fibroblast (HDF) Cell Lines.Molecules. 2016 May 24;21(6).