Liriodenine
| Code | Size | Price |
|---|
| TAR-TN1875-5mg | 5mg | £504.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-TN1875-1mL | 1 mL * 10 mM (in DMSO) | £512.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Liriodenine is a potent inhibitor of topoisomerase II (EC 5.99.1.3) both in vivo and in vitro, it has antitumor, antibacterial and antifungal activities, it can suppress ventricular arrhythmias induced by myocardial ischaemia reperfusion, through inhibition of Na+ and the Ito channel. Liriodenine also has antimuscarinic properties, the antimuscarinic characteristics are similar to those of 4-diphenylacetoxy-N-methylpiperidine (4-DAMP, smooth muscle selective M3 antagonist), it may act as a selective M3 receptor antagonist in canine tracheal smooth muscle.
CAS:
475-75-2
Formula:
C17H9NO3
Molecular Weight:
275.263
Pathway:
Apoptosis; Proteases/Proteasome
Purity:
0.98
SMILES:
O=C1c2ccccc2-c2c3OCOc3cc3ccnc1c23
Target:
BCL; Caspase; p53
References
Liriodenine induces the apoptosis of human laryngocarcinoma cells via the upregulation of p53 expression.Oncol Lett. 2015 Mar;9(3):1121-1127.