TargetMol

Pinoresinol

Product Code:
 
TAR-TN2080
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-TN2080-1mg1mg£138.00
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TAR-TN2080-5mg5mg£213.00
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TAR-TN2080-1mL1 mL * 10 mM (in DMSO)£229.00
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TAR-TN2080-10mg10mg£301.00
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TAR-TN2080-25mg25mg£463.00
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TAR-TN2080-50mg50mg£621.00
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TAR-TN2080-100mg100mg£849.00
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This product comes from: United States.
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Further Information

Bioactivity:
Pinoresinol has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury, to increase nitric oxide release and to reduce oxidative stress preserving pial blood flow distribution; it may exert pharmacologically interesting effects via modulation of the insulin-like signalling pathway in C.elegans. Pinoresinol causes an upregulation of the CDK inhibitor p21(WAF1/Cip1) both at mRNA and protein levels, inhibits NF-kappaB and activating protein 1 (AP-1).
CAS:
487-36-5
Formula:
C20H22O6
Molecular Weight:
358.4
Pathway:
Cell Cycle/Checkpoint; Apoptosis; NF-κb
Purity:
0.9867
SMILES:
COc(cc([C@H]1OC[C@@H]2[C@@H](c(cc3)cc(OC)c3O)OC[C@H]12)cc1)c1O
Target:
Apoptosis; NF-κB; CDK; p53

References

Among plant lignans, pinoresinol has the strongest antiinflammatory properties in human intestinal Caco-2 cells.J Nutr. 2012 Oct;142(10):1798-805.