TargetMol

Saikogenin D

Product Code:
 
TAR-TN2169
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN2169-5mg5mg£264.00
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Quantity:
TAR-TN2169-1mL1 mL * 10 mM (in DMSO)£440.00
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Further Information

Bioactivity:
Saikogenin D possesses a dual effect: an inhibition of A23187-induced PGE2 production without a direct inhibition of cyclooxygenase activity; and an elevation of [Ca2+]i that is attributed to Ca2+ release from intracellular stores. Saikogenin D has immunomodulatory effect, it can attenuate IL-6 production in LPS-stimulated alveolar macrophages of B6 more than in that of BALB.
CAS:
5573-16-0
Formula:
C30H48O4
Molecular Weight:
472.71
Pathway:
Metabolism; Immunology/Inflammation; Membrane transporter/Ion channel; GPCR/G Protein
Purity:
0.98
SMILES:
[H][C@@]12CC[C@]3(C)[C@]([H])(C=CC4=C5CC(C)(C)CC[C@]5(CO)[C@H](O)C[C@@]34C)[C@@]1(C)CC[C@H](O)[C@@]2(C)CO
Target:
IL Receptor; Calcium Channel; Prostaglandin Receptor

References

Dual effect of saikogenin D: in vitro inhibition of prostaglandin E2 production and elevation of intracellular free Ca2+ concentration in C6 rat glioma cells.Planta Medica, 2003, 69(8):765.