TargetMol

Scutebarbatine A

Product Code:
 
TAR-TN2191
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
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CodeSizePrice
TAR-TN2191-5mg5mg£850.00
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Quantity:
TAR-TN2191-1mL1 mL * 10 mM (in DMSO)£1,113.00
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Further Information

Bioactivity:
Scutebarbatine A shows significant antitumor effects on A549 cells in vivo and in vitro via mitochondria-mediated apoptosis by up-regulating expressions of caspase-3 and 9, and down-regulating Bcl-2. Scutebarbatine A and barbatine A show a significant ability to protect cells against H2O2 with ED50 values of 5.0 and 16.8 μM, respectively.
CAS:
176520-13-1
Formula:
C32H34N2O7
Molecular Weight:
558.631
Pathway:
Apoptosis; Proteases/Proteasome
Purity:
0.98
SMILES:
[H][C@]12CCC=C(C)[C@]1(C)[C@@H](OC(=O)c1cccnc1)[C@H](OC(=O)c1cccnc1)[C@](C)(O)[C@]2(C)C=CC1=CC(=O)OC1
Target:
BCL; Caspase

References

In vitro and in vivo antitumor activity of scutebarbatine A on human lung carcinoma A549 cell lines.Molecules. 2014 Jun 25;19(7):8740-51.