Britannilactone diacetate
Code | Size | Price |
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TAR-TN2511-5mg | 5mg | £665.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-TN2511-1mL | 1 mL * 10 mM (in DMSO) | £673.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
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Documents
Further Information
Bioactivity:
1,6-O,O-Diacetylbritannilactone(OODBL) has anti-inflammatory activity, it has a potential therapeutic efficacy on inflammatory diseases especially allergic airway disease as a lead compound. OODBL has anti-asthmatic activity, it reduces leukotriene C4 production and degranulation through the suppression of cytosolic phospholipase A2 phosphorylation and phospholipase Cγ-mediated Ca2+ influx in IgE/antigen-stimulated BMMCs. OODBL also exhibits potent antitumor activity against several human cancer cell lines.
CAS:
1286694-67-4
Formula:
C19H26O6
Molecular Weight:
350.4
Pathway:
Chromatin/Epigenetic; Stem Cells; DNA Damage/DNA Repair; MAPK; Immunology/Inflammation; Proteases/Proteasome; JAK/STAT signaling; Apoptosis; Angiogenesis
Purity:
0.98
SMILES:
C[C@@H](CCCOC(C)=O)C1=C(C)C[C@H]2OC(=O)C(=C)[C@H]2[C@@H]1OC(C)=O
Target:
IL Receptor; PARP; ROS; MAPK; Caspase; JAK; JNK; STAT