2'-Hydroxydaidzein
| Code | Size | Price |
|---|
| TAR-TN2766-1mg | 1mg | £189.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
2'-Hydroxygenistein is an isoflavonoid phytoalexin, it suppresses chemical mediators in inflammatory cells, may have value in treatment and prevention of central and peripheral inflammatory diseases associated with excess production of chemical mediators. 2'-Hydroxygenistein shows significant concentration-dependent inhibitory effects on the release of beta-glucuronidase and lysozyme from rat neutrophils in response to formyl-Met-Leu-Phe/cytochalasin B (fMLP/CB) with IC(50) values of 2.8+/-0.1 and 5.9+/-1.4 microM, respectively.
CAS:
7678-85-5
Formula:
C15H10O5
Molecular Weight:
270.24
Pathway:
Immunology/Inflammation
Purity:
0.98
SMILES:
Oc1ccc(c(O)c1)-c1coc2cc(O)ccc2c1=O
Target:
NADPH-oxidase
References
Fischer D, et al. Phytoalexin synthesis in soybean: purification and characterization of NADPH:2'-hydroxydaidzein oxidoreductase from elicitor-challenged soybean cell cultures. Arch Biochem Biophys. 1990 ; 276(2):390-395.
Ko HH, et al. Anti-inflammatory flavonoids and pterocarpanoid from Crotalaria pallida and C. assamica. Bioorg. Med. Chem. Lett. 2004 ; 14(22):1011-1014.