5-Hydroxy-7,8-dimethoxyflavanone
| Code | Size | Price |
|---|
| TAR-TN3119-5mg | 5mg | £2,151.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
5-Hydroxy-7,8-dimethoxyflavanone is isolated from Andrographis paniculata Nees. leaves and roots with anti-inflammatory activity.
CAS:
113981-49-0
Formula:
C17H16O5
Molecular Weight:
300.3
Pathway:
Microbiology/Virology; Immunology/Inflammation; NF-κb; Proteases/Proteasome; Apoptosis
Purity:
0.98
SMILES:
COc1cc(O)c2C(=O)C[C@H](Oc2c1OC)c1ccccc1
Target:
IL Receptor; TNF; NF-κB; HIV Protease; NO Synthase; CCR
References
Kotewong R, et al. Structure?function relationships of inhibition of mosquito cytochrome P450 enzymes by flavonoids of Andrographis paniculata. Parasitol Res. 2014 Sep;113(9):3381-92.
Chao WW, Kuo YH, Lin BF. Anti-inflammatory activity of new compounds from Andrographis paniculata by NF-kappaB transactivation inhibition. J Agric Food Chem. 2010 Feb 24;58(4):2505-12.