6,4'-Dihydroxy-7-methoxyflavanone
Code | Size | Price |
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TAR-TN3144-1mg | 1mg | £266.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
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Further Information
Bioactivity:
6,4'-Dihydroxy-7-methoxyflavanone is a biologically active compound isolated from the heartwood of Dalbergia odorifera T. Chen (Leguminosae) with antioxidant, anti-inflammatory and neuroprotective effects. 6,4'-Dihydroxy-7-methoxyflavanone can be used in studies about the treatment of osteoclastogenic bone diseases such osteoporosis, rheumatoid arthritis and periodontal diseases.
CAS:
189689-32-5
Formula:
C16H14O5
Molecular Weight:
286.27
Pathway:
GPCR/G Protein; Immunology/Inflammation; MAPK; NF-κb; Autophagy; oxidation-reduction; Apoptosis
Purity:
0.98
SMILES:
COc1cc2O[C@@H](CC(=O)c2cc1O)c1ccc(O)cc1
Target:
ERK; IL Receptor; Antioxidant; TNF; NF-κB; MAPK; Prostaglandin Receptor; JNK; Autophagy
References
Li B, et al. Involvement of heme oxygenase-1 induction in the cytoprotective and immunomodulatory activities of 6,4'-dihydroxy-7-methoxyflavanone in murine hippocampal and microglia cells. Eur J Pharmacol. 2012 Jan 15;674(2-3):153-62.