6-Deoxyjacareubin
| Code | Size | Price |
|---|
| TAR-TN3161-1mg | 1mg | £736.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
6-Deoxyjacareubin possesses significant antioxidant activities, it also exhibits the cytotoxic activities against HL-60, SMMC-7721, A-549, MCF-7, and SW-480 cell lines.6-Deoxyjacareubin is antifungal against Cladosporium cucumerinum, while it shows differing degrees of inhibition of monoamine oxidase A and B. 6-Deoxyjacareubin shows strong platelet activating factor (PAF) receptor binding inhibitory effects using rabbit platelets with IC50 values of 29.0 microM, suggests that xanthones can represent a new class of natural PAF receptor antagonists.
CAS:
16265-56-8
Formula:
C18H14O5
Molecular Weight:
310.3
Pathway:
Microbiology/Virology; GPCR/G Protein
Purity:
0.98
SMILES:
CC1(C)Oc2cc3oc4c(O)cccc4c(=O)c3c(O)c2C=C1
Target:
PAFR; Antifection
References
Antioxidant phenolic compounds of cassava (Manihot esculenta) from Hainan. Molecules. 2011 Dec 7;16(12):10157-67.
Inhibitory effects of xanthones on platelet activating factor receptor binding in vitro. J Ethnopharmacol. 2001 May;75(2-3):287-90.