Griffipavixanthone
| Code | Size | Price |
|---|
| TAR-TN4166-5mg | 5mg | £2,134.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-TN4166-1mL | 1 mL * 10 mM (in DMSO) | £2,543.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Griffipavixanthone inhibits the growth of human Non-small-cell lung cancer H520 cells in dose- and time-dependent manners, it induces cell apoptosis through mitochondrial apoptotic pathway accompanying with ROS production. It can inhibit tumor metastasis and proliferation via downregulation of the RAF pathway in esophageal cancer.
CAS:
219649-95-3
Formula:
C36H28O12
Molecular Weight:
652.6
Pathway:
Immunology/Inflammation; MAPK; Apoptosis; Proteases/Proteasome
Purity:
0.98
SMILES:
CC1=C[C@H]2[C@H]([C@@H](c3c2c2c(oc4cc(O)cc(O)c4c2=O)c(O)c3O)c2cc(O)c(O)c3oc4cc(O)cc(O)c4c(=O)c23)C(C)(C)C1
Target:
ERK; Raf; ROS; MEK; Caspase