TargetMol

Hydrangenol

Product Code:
 
TAR-TN4234
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN4234-1mg1mg£182.00
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TAR-TN4234-5mg5mg£328.00
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TAR-TN4234-1mL1 mL * 10 mM (in DMSO)£336.00
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TAR-TN4234-10mg10mg£455.00
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TAR-TN4234-25mg25mg£701.00
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TAR-TN4234-50mg50mg£938.00
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TAR-TN4234-100mg100mg£1,259.00
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TAR-TN4234-500mg500mg£2,448.00
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Further Information

Bioactivity:
Hydrangenol is isolated from Hydrangea serrata leaves exerts antiphotoaging activity in vitro.
CAS:
480-47-7
Formula:
C15H12O4
Molecular Weight:
256.3
Pathway:
Immunology/Inflammation; Autophagy; Microbiology/Virology; NF-κb
Purity:
0.9902
SMILES:
Oc1ccc(cc1)C1Cc2cccc(O)c2C(=O)O1
Target:
NOS; NF-κB; Nrf2; NO Synthase; Antifection; Autophagy

References

Kim HJ, et al. Hydrangenol inhibits lipopolysaccharide-induced nitric oxide production in BV2 microglial cells by suppressing the NF-?B pathway and activating the Nrf2-mediated HO-1 pathway. Int Immunopharmacol. 2016 Jun;35:61-69. Myung DB, et al. Hydrangenol Isolated from the Leaves of Hydrangea serrata Attenuates Wrinkle Formation and Repairs Skin Moisture in UVB-Irradiated Hairless Mice. Nutrients. 2019 Oct 2;11(10):2354. Gho Y, et al. Hydrangenol suppresses VEGF-stimulated angiogenesis by targeting p27KIP1-dependent G1-cell cycle arrest, VEGFR-2-mediated signaling, and MMP-2 expression. Anim Cells Syst (Seoul). 2019 Feb 14;23(2):72-81.