TargetMol

Kansuinine A

Product Code:
 
TAR-TN4379
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN4379-1mg1mg£205.00
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TAR-TN4379-5mg5mg£401.00
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TAR-TN4379-10mg10mg£563.00
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TAR-TN4379-1mL1 mL * 10 mM (in DMSO)£603.00
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TAR-TN4379-25mg25mg£855.00
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TAR-TN4379-50mg50mg£1,131.00
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Further Information

Bioactivity:
Kansuinine A, a 95% ethanol extract from the roots of E. kansui, possesses an inhibitory effect on IL-6-induced Stat3 activation by activating ERK1/2.
CAS:
57701-86-7
Formula:
C37H46O15
Molecular Weight:
730.8
Pathway:
JAK/STAT signaling; Stem Cells; Immunology/Inflammation
Purity:
0.98
SMILES:
C[C@H]1C[C@@]2(OC(C)=O)C([C@H]1OC(C)=O)[C@@H](OC(C)=O)C(=C)[C@H](OC(C)=O)[C@@H](OC(=O)c1ccccc1)[C@@H](OC(C)=O)C(C)(C)[C@H]1O[C@]2(O)[C@H](C)C1=O
Target:
IL Receptor; STAT; Interleukin

References

Jong Sun Chang, et al. Kansuinine A and Kansuinine B from Euphorbia kansui L. inhibit IL-6-induced Stat3 activation. Planta Med. 2010 Oct;76(14):1544-9. Xiaoyun Shu, et al. Bioassay-guided separation of the proinflammatory constituents from the roots of Euphorbia kansui. J Nat Med. 2010 Jan;64(1):98-103. Stimulation of Nerve Growth Factor Production by Diterpenoids Isolated from Plants of Euphorbia Species. Bioscience, Biotechnology, and Biochemistry.1994 Aug 23:1749-1751.